Mederic Mouterde
PhD
Presentation
My PhD research is focused on the adaptation of modern humans to different chemical environments (including dietary environments) by using a group of genes of great medical interest: drug metabolizing (ADME) genes. This approach involves the collection and generation of both phenotypes and genomics data from diverse and newly sampled human populations.
Publications
de Villemereuil, P., Mouterde, M., Gaggiotti, O. E., & Till‐Bottraud, I. (2018). Patterns of phenotypic plasticity and local adaptation in the wide elevation range of the alpine plant Arabis alpina. Journal of Ecology (https://doi.org/10.1111/1365-2745.12955).
de Villemereuil, P., Gaggiotti, O. E., Mouterde, M., & Till-Bottraud, I. (2016). Common garden experiments in the genomic era: new perspectives and opportunities. Heredity, 116(3), 249.
Rollason V.*, Mouterde M.*, Daali Y., Cizkova M., Priehodová E., Kulichova I., Posova H., Petanova J., Mulugeta A., Makonnen E., Davidson R., Al-Balushi K., Al-Thihli K., Cerna M., Al-Yahyaee S., Cerny V., Yimer G., Poloni E. S. & Desmeules J. (to be submitted). Safety of the Geneva cytochrome P450 and glycoprotein-P phenotyping micrococktail in healthy volunteers from three different geographic origins.* equally contributed
Vangenot, C., Gagneux P., de Groot N., Baumeyer A., Mouterde M., Crouau-Roy B., Darlu P., Sanchez-Mazas A., Sabbagh A., Poloni E. S. (to be submitted). Humans and chimpanzees display opposite patterns of diversity in arylamine N-acetyltranferase genes.
Mouterde M., Daali Y., Rollason V., Al-Yahyaee S., Boukouvala S., Yimer G., Černý V., Desmeules J. & Poloni E. S. (in prep.). Analysis of population structure between Africa and Europe reveals unexpected high genomic diversity in a homogenous human population.
